Then, your dosage will be adjusted as needed. To do so, you will have regular tests to determine how fast your blood will clot based on a scale called the International Normalized Ratio (INR). Instead, your doctor will decide your dose based on how you respond to it. Unlike most drugs, there is no one-size-fits-all dose for warfarin. For this reason, warfarin is often referred to as a Vitamin K antagonist. Warfarin works by blocking this action, thus preventing clots that could cause a stroke. Your body needs vitamin K to form blood clots. Other names for warfarin include Jantoven ®, Marevan ®, Lawarin ®, Waran ®, and Warfant ®. Warfarin is generally recommended for those with valvular afib (defined as a mechanical heart valve or moderate-to-severe mitral stenosis) due to direct oral anticoagulants not being well studied for those with valvular afib. It was approved as a medication in 1954 and is now widely prescribed for preventing strokes from atrial fibrillation. Discovered in the 1940s by a scientist at the University of Wisconsin-Madison, it was originally used as a rat poison. Warfarin is the oldest oral anticoagulant available, with more than 50 years of studies attesting to its effectiveness and safety. It is often called a “blood thinner” and is frequently prescribed for people with atrial fibrillation to prevent a stroke. Warfarin (Coumadin ®) is an anticoagulant medication that interferes with the blood’s ability to clot.
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